QSAR analysis and molecular docking simulation of norepinephrine transporter (NET) inhibitors as anti-psychotic therapeutic agents

The norepinephrine transporter (NET) is a Na+/Cl− coupled neurotransmitter transporter responsible for reuptake of released norepinephrine (NE) into nerve terminals in the brain, a key therapeutic used in the treatment of psychiatric disorders. A quantitative structural activity relationship (QSAR)...

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Bibliographic Details
Main Authors: Sabitu Babatunde Olasupo, Adamu Uzairu, Gideon Shallangwa, Sani Uba
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844019363005