Establishing adherence–concentration–efficacy thresholds of TDF–FTC pre-exposure prophylaxis for HIV prevention in African women: a protocol for the Women TDF–FTC Benchmark Study

Establishing adherence–concentration–efficacy thresholds of TDF–FTC pre-exposure prophylaxis for HIV prevention in African women: a protocol for the Women TDF–FTC Benchmark Study

BackgroundOral pre-exposure prophylaxis (PrEP) using co-formulated emtricitabine (FTC) and tenofovir disoproxil fumarate (TDF) is a potent HIV prevention method for men and women, with its efficacy highly dependent on adherence. A pivotal HIV efficacy study combined with a directly observed pharmaco...

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Bibliographic Details
Main Authors: Linxuan Wu, Matilda Saina, Clare Brown, David Chege, Deborah Donnell, David V. Glidden, Kenneth Ngure, Nelly R. Mugo, Nina Akelo, Torin Schaafsma, Peter L. Anderson, Kenneth K. Mugwanya
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Reproductive Health
Subjects:
HIV pre-exposure prophylaxis
cisgender women
adherence
pharmacokinetics
efficacy
Online Access:https://www.frontiersin.org/articles/10.3389/frph.2024.1325257/full

Internet

https://www.frontiersin.org/articles/10.3389/frph.2024.1325257/full

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