The in-silico feasibility of dose escalated, hypofractionated radiotherapy for rectal cancer

The in-silico feasibility of dose escalated, hypofractionated radiotherapy for rectal cancer

Background and purpose: Short course radiotherapy (SCRT) has a low biological prescription dose. Rectal cancer has a dose response relationship and moderate α/β ratio (∼5). We hypothesise hypofractionated dose escalation has radiobiological advantages. We assessed in-silico dose escalation to the pr...

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Bibliographic Details
Main Authors: Lynsey Devlin, Laura Grocutt, Bianca Hunter, Hiwot Chemu, Aileen Duffton, Alec McDonald, Nicholas Macleod, Philip McLoone, Sean M. O'Cathail
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Clinical and Translational Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630822000489

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http://www.sciencedirect.com/science/article/pii/S2405630822000489

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