The Role and Mechanism of Lysine Methyltransferase and Arginine Methyltransferase in Kidney Diseases

Methylation can occur in both histones and non-histones. Key lysine and arginine methyltransferases under investigation for renal disease treatment include enhancer of zeste homolog 2 (EZH2), G9a, disruptor of telomeric silencing 1-like protein (DOT1L), and protein arginine methyltransferases (PRMT)...

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Bibliographic Details
Main Authors: Xun Zhou, Hui Chen, Jinqing Li, Yingfeng Shi, Shougang Zhuang, Na Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.885527/full