Amyloid-polysaccharide interfacial coacervates as therapeutic materials

Liquid-liquid phase separation offer a strategy for targeting biomaterial scaffolds, but controlling assembly to form functional materials is challenging. Here, the authors transform native proteins into amyloid fibres for assembly, and use the materials as a gastric ulcer protective agent.

Bibliographic Details
Main Authors: Mohammad Peydayesh, Sabrina Kistler, Jiangtao Zhou, Viviane Lutz-Bueno, Francesca Damiani Victorelli, Andréia Bagliotti Meneguin, Larissa Spósito, Tais Maria Bauab, Marlus Chorilli, Raffaele Mezzenga
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37629-z