Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3ß and CDK5 following traumatic brain injury

Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3ß and CDK5 following traumatic brain injury

Aberrant ion channel function has been heralded as a main underlying mechanism driving epilepsy and its symptoms. However, it has become increasingly clear that treatment strategies targeting voltage-gated sodium or calcium channels merely mask the symptoms of epilepsy without providing disease-mod...

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Bibliographic Details
Main Authors: Sarah Marie Wilson, Seul eKi Yeon, Xiao-Fang eYang, Ki Duk ePark, Rajesh eKhanna
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Phosphorylation
Epileptogenesis
mossy fiber sprouting
CDK5
CRMP2
GSK3β
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00135/full

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http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00135/full

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