Targeted screening and identification of chlorhexidine as a pro-myogenic circadian clock activator

Targeted screening and identification of chlorhexidine as a pro-myogenic circadian clock activator

Abstract Background The circadian clock is an evolutionarily conserved mechanism that exerts pervasive temporal control in stem cell behavior. This time-keeping machinery is required for orchestrating myogenic progenitor properties in regenerative myogenesis that ameliorates muscular dystrophy. Here...

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Bibliographic Details
Main Authors: Tali Kiperman, Weini Li, Xuekai Xiong, Hongzhi Li, David Horne, Ke Ma
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Stem Cell Research & Therapy
Subjects:
Muscle stem cell
Myogenic progenitor
Myogenesis
Myoblast differentiation
Circadian clock
Small molecule
Online Access:https://doi.org/10.1186/s13287-023-03424-2

Internet

https://doi.org/10.1186/s13287-023-03424-2

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