Ginseng total saponins rescue susceptibility to adult depression-like behaviors in mice induced by early-life stress via regulating CREB/BDNF/TrkB signaling

Ginseng total saponins rescue susceptibility to adult depression-like behaviors in mice induced by early-life stress via regulating CREB/BDNF/TrkB signaling

ABSTRACTIn this study, mice undergoing either short maternal separation (MS) or long MS during early postnatal life and then experiencing chronic unpredictable mild stress (CUMS) in adulthood were established to explore the critical mechanism of the ginseng total saponins (GTS), extractions of ginse...

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Bibliographic Details
Main Authors: Yaoyao Bian, Lili Yang, Yutong Wang, Ping Lu, Wen Li, Jia Miao, Yiting Gong, Bin Zhang, Yanyun Yin
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:CyTA - Journal of Food
Subjects:
Ginseng total saponins
early-life stress
chronic unpredictable mild stress
susceptibility
CREB/BDNF/TrkB pathway
Online Access:https://www.tandfonline.com/doi/10.1080/19476337.2023.2277844

Internet

https://www.tandfonline.com/doi/10.1080/19476337.2023.2277844

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