RILP inhibits tumor progression in osteosarcoma via Grb10-mediated inhibition of the PI3K/AKT/mTOR pathway

RILP inhibits tumor progression in osteosarcoma via Grb10-mediated inhibition of the PI3K/AKT/mTOR pathway

Abstract Background Rab-interacting lysosomal protein (RILP) contains an alpha-helical coil with an unexplored biological function in osteosarcoma. This study investigated the expression of RILP in osteosarcoma cells and tissues to determine the effect of RILP on the biological behaviors of osteosar...

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Bibliographic Details
Main Authors: Zhun Wei, Kezhou Xia, Di Zheng, Changtian Gong, Weichun Guo
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Molecular Medicine
Subjects:
RILP
Osteosarcoma
Autophagy
Epithelial–mesenchymal transition
Online Access:https://doi.org/10.1186/s10020-023-00722-6

Internet

https://doi.org/10.1186/s10020-023-00722-6

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