JAML immunotherapy targets recently activated tumor-infiltrating CD8+ T cells

JAML immunotherapy targets recently activated tumor-infiltrating CD8+ T cells

Summary: Junctional adhesion molecule-like protein (JAML) serves as a co-stimulatory molecule in γδ T cells. While it has recently been described as a cancer immunotherapy target in mice, its potential to cause toxicity, specific mode of action with regard to its cellular targets, and whether it can...

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Bibliographic Details
Main Authors: Simon Eschweiler, Alice Wang, Ciro Ramírez-Suástegui, Adrian von Witzleben, Yingcong Li, Serena J. Chee, Hayley Simon, Monalisa Mondal, Matthew Ellis, Gareth J. Thomas, Vivek Chandra, Christian H. Ottensmeier, Pandurangan Vijayanand
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Cell Reports
Subjects:
CP: Cancer
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723000517

Internet

http://www.sciencedirect.com/science/article/pii/S2211124723000517

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