Synthesis and antifungal activities of novel trifluoroethane derivatives with coumarin, indole and thiophene

Synthesis and antifungal activities of novel trifluoroethane derivatives with coumarin, indole and thiophene

A series of novel 1-(β-coumarinyl)-1-(β-indolyl)-1-(α-thiophenyl)trifluoroethane derivatives 5aaa-5hdb were prepared by one-pot reaction from 3-(trifluoroacetyl)coumarin with indole and α-substituted thiophene. Their structures were confirmed by 1H NMR, 13C NMR, 19F NMR, HRMS and X-ray single crysta...

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Bibliographic Details
Main Authors: Bingyi Zhou, Xinxin Yuan, Liangxin Fan, Zhenliang Pan, Xiaodan Chang, Shengfei Jiang, Lulu Wu, Caixia Wang, Guoyu Yang, Xiaoming Ji, Lijun Shi, Cuilian Xu
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Journal of Saudi Chemical Society
Subjects:
Coumarin
Thiophene
Trifluoromethyl
Antifungal activity
One-pot reaction
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610322001545

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http://www.sciencedirect.com/science/article/pii/S1319610322001545

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