Study of the decorporation efficacy and toxicity of tetradentate 3-hydroxy-2-pyridinone ligands at the cellular level

Study of the decorporation efficacy and toxicity of tetradentate 3-hydroxy-2-pyridinone ligands at the cellular level

Objective: A series of experiments were carried out to study the comparative decorporation efficacy and toxicity of three tetradentate hydroxypyridinone ligands (3LI-1-Cm-3,2-HOPO, 5LIO-1-Cm-3,2-HOPO, and 7LIO-1-Cm-3,2-HOPO) with the variation of the linker length and the substituents. Methods: Thre...

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Bibliographic Details
Main Authors: Xiaomei Wang, Cen Shi, Manni Gao, Ying Xu, Yang Jiao, Jianmei Wan, Jianping Cao, Zhifang Chai, Juan Diwu
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Radiation Medicine and Protection
Subjects:
Uranium
Hydroxypyridinone
Decorporation efficacy
Cytotoxicity
Metal complexation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666555720300666

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http://www.sciencedirect.com/science/article/pii/S2666555720300666

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