Sestrin2 in cancer: a foe or a friend?
Abstract Sestrin2 is a conserved antioxidant, metabolism regulator, and downstream of P53. Sestrin2 can suppress oxidative stress and inflammation, thereby preventing the development and progression of cancer. However, Sestrin2 attenuates severe oxidative stress by activating nuclear factor erythroi...
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | Biomarker Research |
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| Online Access: | https://doi.org/10.1186/s40364-022-00380-6 |