Phylogenetic inference from single-cell RNA-seq data

Abstract Tumors are comprised of subpopulations of cancer cells that harbor distinct genetic profiles and phenotypes that evolve over time and during treatment. By reconstructing the course of cancer evolution, we can understand the acquisition of the malignant properties that drive tumor progressio...

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Bibliographic Details
Main Authors: Xuan Liu, Jason I. Griffiths, Isaac Bishara, Jiayi Liu, Andrea H. Bild, Jeffrey T. Chang
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39995-6