Immunogenicity of Tumor Initiating Stem Cells: Potential Applications in Novel Anticancer Therapy

Tumor initiating stem cells (TISCs) are a subset of tumor cells, which are implicated in cancer relapse and resistance to chemotherapy. The metabolic programs that drive TISC functions are exquisitely unique and finely-tuned by various oncogene-driven transcription factors to facilitate pro-cancerou...

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Bibliographic Details
Main Authors: Durga Khandekar, Suneetha Amara, Venkataswarup Tiriveedhi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00315/full