Mitotic activity index and CD25+ lymphocytes predict risk of stage progression in non-muscle invasive bladder cancer.

In urothelial cell type non-muscle invasive urinary bladder carcinoma, TNM stage and WHO grade are widely used to classify patients into low and high‑risk groups for prognostic and therapeutic decision-making. However, stage and grade reproducibility and prediction accuracy are wanting. This may lea...

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Main Authors: Melinda Lillesand, Vebjørn Kvikstad, Ok Målfrid Mangrud, Einar Gudlaugsson, Bianca van Diermen-Hidle, Ivar Skaland, Jan P A Baak, Emiel A M Janssen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233676