P-coumaric acid ameliorates Aβ25–35-induced brain damage in mice by modulating gut microbiota and serum metabolites

P-coumaric acid ameliorates Aβ25–35-induced brain damage in mice by modulating gut microbiota and serum metabolites

Alzheimer's disease (AD) is a progressive neurodegenerative disease for which there is a lack of effective therapeutic drugs. There is great potential for natural products to be used in the development of anti-AD drugs. P-coumaric acid (PCA), a small molecule phenolic acid widely distributed in...

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Bibliographic Details
Main Authors: Bing Cao, Meng-nan Zeng, Feng-xiao Hao, Zhi-you Hao, Zhen-kai Zhang, Xi-wen Liang, Yuan-yuan Wu, Yu-han Zhang, Wei-sheng Feng, Xiao-ke Zheng
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Alzheimer's disease
P-coumaric acid
Gut microbiomics
Serum metabolomics
Neuroinflammation
Glucose metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223016232

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http://www.sciencedirect.com/science/article/pii/S0753332223016232

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