Antioxidant and anti-inflammatory activities of Centratherum anthelminticum (L.) Kuntze seed oil in diabetic nephropathy via modulation of Nrf-2/HO-1 and NF-κB pathway

Antioxidant and anti-inflammatory activities of Centratherum anthelminticum (L.) Kuntze seed oil in diabetic nephropathy via modulation of Nrf-2/HO-1 and NF-κB pathway

Abstract Background Type 2 diabetes mellitus (T2DM) approximately constitutes 90% of the reported cases. 30-40% of diabetics eventually develop diabetic nephropathy (DN); accounting for one of the major causes of morbidity and mortality. Increased glucose autoxidation and non-enzymatic glycation of...

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Bibliographic Details
Main Authors: Nida Baig, Rabia Sultan, Shamim Akhtar Qureshi
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Centratherum anthelminticum
Fixed oil
Diabetes mellitus
Nephropathy
Nrf-2/Keap1/HO-1
NF-κB
Online Access:https://doi.org/10.1186/s12906-022-03776-x

Internet

https://doi.org/10.1186/s12906-022-03776-x

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