Contrary effects of the gut metabolites deoxycholate and butyrate on the acetylcholine-evoked calcium response in an enteroendocrine cell model

The interaction of nutrients and bacterial-derived products and their enteroendocrine effects are still enigmatic. We used the human enteroendocrine tumour cell line P-STS isolated from the terminal ileum as cellular sentinel. In this model, P-STS cells react to acetylcholine or histamine with an in...

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Bibliographic Details
Main Authors: Beatrix Pfanzagl, Erika Jensen-Jarolim
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Endocrine and Metabolic Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666396124000116