The Role of Sirtuin 3 in Radiation-Induced Long-Term Persistent Liver Injury

In patients with abdominal region cancers, ionizing radiation (IR)-induced long-term liver injury is a major limiting factor in the use of radiotherapy. Previously, the major mitochondrial deacetylase, sirtuin 3 (SIRT3), has been implicated to play an important role in the development of acute liver...

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Bibliographic Details
Main Authors: Francesca V. LoBianco, Kimberly J. Krager, Gwendolyn S. Carter, Sinthia Alam, Youzhong Yuan, Elise G. Lavoie, Jonathan A. Dranoff, Nukhet Aykin-Burns
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/9/5/409