Caloric restriction protects against electrical kindling of the amygdala by inhibiting the mTOR signaling pathway

Caloric restriction protects against electrical kindling of the amygdala by inhibiting the mTOR signaling pathway

Caloric restriction (CR) has been shown to possess antiepileptic properties; however its mechanism of action is poorly understood. CR might inhibit the activity of the mammalian or mechanistic target of rapamycin (mTOR) signaling cascade, which seems to participate crucially in the generation of epi...

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Bibliographic Details
Main Authors: Bryan Victor Phillips-Farfan, María del Carmen eRubio Osornio, Verónica eCustodio Ramírez, Carlos ePaz Tres, Karla Guadalupe Carvajal
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Caloric Restriction
Epilepsy
Hippocampus
Neocortex
mTOR signaling cascade
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00090/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00090/full

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