Cell surface-localized CsgF condensate is a gatekeeper in bacterial curli subunit secretion
Abstract Curli are functional amyloids present on the outer membrane of E. coli. CsgF is required for the proper assembly of curli. Here, we found that the CsgF phase separates in vitro and that the ability of CsgF variants to phase-separate is tightly correlated with CsgF function during curli biog...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-04-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-38089-1 |