Inhibition of USP14 suppresses ferroptosis and inflammation in LPS-induced goat mammary epithelial cells through ubiquitylating the IL-6 protein
Abstract Background Ferroptosis, a novel manner of cell death depended on iron ion, contributed to goat mammary epithelial cell dysfunction. Interleukin-6 (IL-6) is a major pro-inflammatory factor during many inflammation-related diseases including mastitis, and a quite recently identified ferroptos...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-05-01
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Series: | Hereditas |
Subjects: | |
Online Access: | https://doi.org/10.1186/s41065-022-00235-y |