Local euchromatin enrichment in lamina-associated domains anticipates their repositioning in the adipogenic lineage

Local euchromatin enrichment in lamina-associated domains anticipates their repositioning in the adipogenic lineage

Abstract Background Interactions of chromatin with the nuclear lamina via lamina-associated domains (LADs) confer structural stability to the genome. The dynamics of positioning of LADs during differentiation, and how LADs impinge on developmental gene expression, remains, however, elusive. Results...

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Bibliographic Details
Main Authors: Julia Madsen-Østerbye, Mohamed Abdelhalim, Marie-Odile Baudement, Philippe Collas
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Genome Biology
Subjects:
Adipose stem cell
Adipogenesis
Enhancer
H3K27 acetylation
LAD
Lamina-associated domain
Online Access:https://doi.org/10.1186/s13059-022-02662-6

Internet

https://doi.org/10.1186/s13059-022-02662-6

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