Exploring the role of pyroptosis in shaping the tumor microenvironment of colorectal cancer by bulk and single-cell RNA sequencing

Exploring the role of pyroptosis in shaping the tumor microenvironment of colorectal cancer by bulk and single-cell RNA sequencing

Abstract Background Emerging studies have shown that pyroptosis plays a non-negligible role in the development and treatment of tumors. However, the mechanism of pyroptosis in colorectal cancer (CRC) remains still unclear. Therefore, this study investigated the role of pyroptosis in CRC. Methods A p...

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Bibliographic Details
Main Authors: Chengsheng Ding, Xiao Yang, Shuchun Li, Enkui Zhang, Xiaodong Fan, Ling Huang, Zirui He, Jing Sun, Junjun Ma, Lu Zang, Minhua Zheng
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Cancer Cell International
Subjects:
Colorectal cancer
Pyroptosis
Tumor microenvironments
Immunotherapy
Single-cell analysis
Online Access:https://doi.org/10.1186/s12935-023-02897-8

Internet

https://doi.org/10.1186/s12935-023-02897-8

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