Development and validation of an Onchocerca ochengi adult male worm gerbil model for macrofilaricidal drug screening.

<h4>Background</h4>Onchocerciasis currently afflicts an estimated 15 million people and is the second leading infectious cause of blindness world-wide. The development of a macrofilaricide to cure the disease has been hindered by the lack of appropriate small laboratory animal models. Th...

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Bibliographic Details
Main Authors: Fidelis Cho-Ngwa, Glory Enjong Mbah, Rene Bilingwe Ayiseh, Emmanuel Menang Ndi, Elvis Monya, Irene Memeh Tumanjong, Evans Ngandung Mainsah, Judy Sakanari, Sara Lustigman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007556