Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10

Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10

OAT10 (SLC22A13) is a transporter highly expressed in renal tubules and transporting organic anions including nicotinate, β-hydroxybutyrate, p-aminohippurate, and orotate. In transport assays using Xenopus oocytes and HEK293 cells, we found that apparent substrate selectivity of OAT10 was different...

Full description

Bibliographic Details
Main Authors: Naoko Ohtsu, Ryuichi Ohgaki, Chunhuan Jin, Minhui Xu, Hiroki Okanishi, Ryo Takahashi, Akiko Matsui, Wataru Kishimoto, Naoki Ishiguro, Yoshikatsu Kanai
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Journal of Pharmacological Sciences
Subjects:
Organic anion
Monocarboxylate
Transporter
Functional coupling
Exogenous expression system
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861322000482

Internet

http://www.sciencedirect.com/science/article/pii/S1347861322000482

Similar Items