GJB2 and GJB6 gene transcripts in the human cochlea: A study using RNAscope, confocal, and super-resolution structured illumination microscopy
BackgroundGap junction (GJ) proteins, connexin26 and 30, are highly prevalent in the human cochlea (HC), where they are involved in transcellular signaling, metabolic supply, and fluid homeostasis. Their genes, GJB2 and GJB6, are both located at the DFNB1 locus on chromosome 13q12. Mutations in GJB2...
Main Authors: | , |
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2022-09-01
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Series: | Frontiers in Molecular Neuroscience |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fnmol.2022.973646/full |