Serum galactose-deficient-IgA1 and IgG autoantibodies correlate in patients with IgA nephropathy.

Serum galactose-deficient-IgA1 and IgG autoantibodies correlate in patients with IgA nephropathy.

IgA nephropathy is an autoimmune disease characterized by IgA1-containing glomerular immune deposits. We previously proposed a multi-hit pathogenesis model in which patients with IgA nephropathy have elevated levels of circulatory IgA1 with some O-glycans deficient in galactose (Gd-IgA1, autoantigen...

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Bibliographic Details
Main Authors: William J Placzek, Hiroyuki Yanagawa, Yuko Makita, Matthew B Renfrow, Bruce A Julian, Dana V Rizk, Yusuke Suzuki, Jan Novak, Hitoshi Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5764330?pdf=render

Internet

http://europepmc.org/articles/PMC5764330?pdf=render

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