Nanoparticle-based itaconate treatment recapitulates low-cholesterol/low-fat diet-induced atherosclerotic plaque resolution

Summary: Current pharmacologic treatments for atherosclerosis do not completely protect patients; additional protection can be achieved by dietary modifications, such as a low-cholesterol/low-fat diet (LCLFD), that mediate plaque stabilization and inflammation reduction. However, this lifestyle modi...

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Bibliographic Details
Main Authors: Natalie E. Hong, Alice Chaplin, Lin Di, Anastasia Ravodina, Graham H. Bevan, Huiyun Gao, Courteney Asase, Roopesh Singh Gangwar, Mark J. Cameron, Matthew Mignery, Olga Cherepanova, Aloke V. Finn, Lalitha Nayak, Andrew A. Pieper, Andrei Maiseyeu
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724012622