Expression of mTOR in normal and pathological conditions
Abstract The mechanistic/mammalian target of rapamycin (mTOR), a protein discovered in 1991, integrates a complex pathway with a key role in maintaining cellular homeostasis. By comprising two functionally distinct complexes, mTOR complex 1 (mTORC1) and mTORC2, it is a central cellular hub that inte...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-07-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12943-023-01820-z |