Expression of mTOR in normal and pathological conditions

Abstract The mechanistic/mammalian target of rapamycin (mTOR), a protein discovered in 1991, integrates a complex pathway with a key role in maintaining cellular homeostasis. By comprising two functionally distinct complexes, mTOR complex 1 (mTORC1) and mTORC2, it is a central cellular hub that inte...

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Bibliographic Details
Main Authors: A Marques-Ramos, R Cervantes
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Molecular Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12943-023-01820-z