Dual-Reporter Mycobacteriophages (Φ<sup>2</sup>DRMs) Reveal Preexisting <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Persistent Cells in Human Sputum

Dual-Reporter Mycobacteriophages (Φ<sup>2</sup>DRMs) Reveal Preexisting <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Persistent Cells in Human Sputum

ABSTRACT Persisters are the minor subpopulation of bacterial cells that lack alleles conferring resistance to a specific bactericidal antibiotic but can survive otherwise lethal concentrations of that antibiotic. In infections with Mycobacterium tuberculosis, such persisters underlie the need for lo...

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Bibliographic Details
Main Authors: Paras Jain, Brian C. Weinrick, Eric J. Kalivoda, Hui Yang, Vanisha Munsamy, Catherine Vilcheze, Torin R. Weisbrod, Michelle H. Larsen, Max R. O’Donnell, Alexander Pym, William R. Jacobs
Format: Article
Language:English
Published: American Society for Microbiology 2016-11-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01023-16

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https://journals.asm.org/doi/10.1128/mBio.01023-16

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