Composition of Challenge Substance in Standardized Antimicrobial Efficacy Testing of Wound Antimicrobials Is Essential to Correctly Simulate Efficacy in the Human Wound Micro-Environment

Composition of Challenge Substance in Standardized Antimicrobial Efficacy Testing of Wound Antimicrobials Is Essential to Correctly Simulate Efficacy in the Human Wound Micro-Environment

Current standards insufficiently acknowledge the influence of the wound micro-environment on the efficacy of antimicrobial agents. To address this, octenidine/phenoxyethanol, polyhexanide, povidone-iodine, and sodium-hypochloride/hypochlorous acid solutions were submitted to standard-based (DIN-EN-1...

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Bibliographic Details
Main Authors: Anna-Lena Severing, Mia Borkovic, Ewa K. Stuermer, Julian-Dario Rembe
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomedicines
Subjects:
antimicrobials
antiseptics
wound infection
organic challenge
wound exudate
DIN-EN-13727
Online Access:https://www.mdpi.com/2227-9059/10/11/2751

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https://www.mdpi.com/2227-9059/10/11/2751

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