Complexation of Z-ligustilide with hydroxypropyl-β-cyclodextrin to improve stability and oral bioavailability
To improve the stability and oral bioavailability of Z-ligustilide (LIG), the inclusion complex of LIG with hydroxypropyl- β-cyclodextrin (HP-β-CD) was prepared by the kneading method and characterized by UV-Vis spectroscopy, differential thermal analysis (DTA) and Fourier transform infrared (FTIR)...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2014-06-01
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Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | http://www.degruyter.com/view/j/acph.2014.64.issue-2/acph-2014-0012/acph-2014-0012.xml?format=INT |