Synergic treatment of Alzheimer’s disease with brain targeted nanoparticles incorporating NgR-siRNA and brain derived neurotrophic factor
The decrease and functional failure of the central cholinergic neurons caused by degeneration and necrosis, not only directly led to a series of clinical symptoms of Alzheimer’s disease (AD), but also seriously affected the efficacy of cholinesterase inhibitors. At present, the clinical treatment of...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2020-01-01
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| Series: | Smart Materials in Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590183420300120 |