Maternal Hyperhomocysteinemia Disturbs the Mechanisms of Embryonic Brain Development and Its Maturation in Early Postnatal Ontogenesis

Maternal Hyperhomocysteinemia Disturbs the Mechanisms of Embryonic Brain Development and Its Maturation in Early Postnatal Ontogenesis

Maternal hyperhomocysteinemia causes the disruption of placental blood flow and can lead to serious disturbances in the formation of the offspring’s brain. In the present study, the effects of prenatal hyperhomocysteinemia (PHHC) on the neuronal migration, neural tissue maturation, and the expressio...

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Bibliographic Details
Main Authors: Dmitrii S. Vasilev, Anastasiia D. Shcherbitskaia, Natalia L. Tumanova, Anastasiia V. Mikhel, Yulia P. Milyutina, Anna A. Kovalenko, Nadezhda M. Dubrovskaya, Daria B. Inozemtseva, Irina V. Zalozniaia, Alexander V. Arutjunyan
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
homocysteine
electron microscopy
neurotrophins
semaphorin
caspase
matrix metalloproteinase
Online Access:https://www.mdpi.com/2073-4409/12/1/189

Internet

https://www.mdpi.com/2073-4409/12/1/189

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