The critical roles of mitophagy in cerebral ischemia

ABSTRACT Mitochondria play a key role in various cell processes including ATP production, Ca2 + homeostasis, reactive oxygen species (ROS) generation, and apoptosis. The selective removal of impaired mitochondria by autophagosome is known as mitophagy. Cerebral ischemia is a common form of stroke ca...

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Bibliographic Details
Main Authors: Yan-Cheng Tang, Hong-Xia Tian, Tao Yi, Hu-Biao Chen
Format: Article
Language:English
Published: Oxford University Press 2016-08-01
Series:Protein & Cell
Subjects:
Online Access:http://link.springer.com/article/10.1007/s13238-016-0307-0