Genome-Wide Association Analysis across Endophenotypes in Alzheimer’s Disease: Main Effects and Disease Stage-Specific Interactions

Genome-Wide Association Analysis across Endophenotypes in Alzheimer’s Disease: Main Effects and Disease Stage-Specific Interactions

The underlying genetic susceptibility for Alzheimer’s disease (AD) is not yet fully understood. The heterogeneous nature of the disease challenges genetic association studies. Endophenotype approaches can help to address this challenge by more direct interrogation of biological traits related to the...

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Bibliographic Details
Main Authors: Thea J. Rosewood, Kwangsik Nho, Shannon L. Risacher, Sujuan Gao, Li Shen, Tatiana Foroud, Andrew J. Saykin, on behalf of the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Genes
Subjects:
genetics
GWAS
endophenotype
APOE
genetic interaction
cerebrospinal fluid biomarkers
Online Access:https://www.mdpi.com/2073-4425/14/11/2010

Internet

https://www.mdpi.com/2073-4425/14/11/2010

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