Repositioning of Dantrolene as a Multitarget Agent for Neurodegenerative Diseases

Repositioning of Dantrolene as a Multitarget Agent for Neurodegenerative Diseases

Dantrolene is an orphan drug representing the sole therapeutic treatment for malignant hyperthermia, a life-threatening pathology affecting 0.2 in every 10,000 people in the EU. [...]

Bibliographic Details
Main Authors: Isabella Bolognino, Marco Catto, Leonardo Pisani, Saverio Cellamare, Cosimo D. Altomare, Nicola Giangregorio
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Proceedings
Subjects:
dantrolene
neurodegenerative diseases
multitarget agents
MAO inhibitors
AChE inhibitors
carnitine translocation
Online Access:https://www.mdpi.com/2504-3900/22/1/7

Internet

https://www.mdpi.com/2504-3900/22/1/7

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