Principles of Effective and Robust Innate Immune Response to Viral Infections: A Multiplex Network Analysis

The human innate immune response, particularly the type-I interferon (IFN) response, is highly robust and effective first line of defense against virus invasion. IFN molecules are produced and secreted from infected cells upon virus infection and recognition. They then act as signaling/communication...

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Bibliographic Details
Main Authors: Yufan Huang, Huaiyu Dai, Ruian Ke
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01736/full