The role of PrPc in Alzheimer's disease related Amyloid-β hypothesis: a systematic review
Alzheimer's disease (AD) is characterized mainly by the accumulation of Amyloid-β oligomers (Aβo) in the brain that leads to hyperphosphorylation and polymerization of the Tau protein in neurofibrillary tangles, which is associated with neuronal death. The initial stage of the disease is due to...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-09-01
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| Series: | Brain Disorders |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666459323000355 |