Comprehensive analysis of androgen receptor status in prostate cancer with neuroendocrine differentiation

Comprehensive analysis of androgen receptor status in prostate cancer with neuroendocrine differentiation

The androgen receptor (AR) signaling is a key contributor to tumorigenesis and the progression of prostate cancer. A subset of patients may develop neuroendocrine (NE) features, resulting in resistance to androgen deprivation therapy and poor prognosis. In this study, we combined immunostaining and...

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Bibliographic Details
Main Authors: Ruopeng Su, Lei Chen, Zhou Jiang, Minghao Yu, Weiwei Zhang, Zehua Ma, Yiyi Ji, Kai Shen, Zhixiang Xin, Jun Qi, Wei Xue, Qi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
androgen receptor
neuroendocrine differentiation
immunohistochemistry
multiplex immunofluorescence
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.955166/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.955166/full

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