Vaccination against Epstein–Barr Latent Membrane Protein 1 Protects against an Epstein–Barr Virus-Associated B Cell Model of Lymphoma

In this study, we demonstrate that expression of viral latent membrane protein 1 (LMP1) in a mouse B cell line renders the animals responsive to protection from a 38C13-LMP1 tumor challenge with a novel vaccine. The Epstein–Barr virus (EBV) preferentially infects circulating B lymphocytes, has oncog...

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Bibliographic Details
Main Authors: Wesley I. Soo Hoo, Kaylie Higa, Alison A. McCormick
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/7/983