Dependence of human cell survival and proliferation on the CASP3 prodomain

Abstract Mechanisms that regulate cell survival and proliferation are important for both the development and homeostasis of normal tissue, and as well as for the emergence and expansion of malignant cell populations. Caspase-3 (CASP3) has long been recognized for its proteolytic role in orchestratin...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Ebrahim Eskandari, Gian Luca Negri, Susanna Tan, Margarita E. MacAldaz, Shengsen Ding, Justin Long, Karina Nielsen, Sandra E. Spencer, Gregg B. Morin, Connie J. Eaves
Format: Artykuł
Język:English
Wydane: Nature Publishing Group 2024-02-01
Seria:Cell Death Discovery
Dostęp online:https://doi.org/10.1038/s41420-024-01826-6