Nicotine Effects and the Endogenous Opioid System

Abstract.: Nicotine (NIC) is an exogenous ligand of the nicotinic acetylcholine receptor (nAChR), and it influences various functions in the central nervous system. Systemic administration of NIC elicits the release of endogenous opioids (endorphins, enkephalins, and dynorphins) in the supraspinal c...

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Bibliographic Details
Main Authors: Shiroh Kishioka, Norikazu Kiguchi, Yuka Kobayashi, Fumihiro Saika
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319301331