USP7 promotes non‐small‐cell lung cancer cell glycolysis and survival by stabilizing and activating c‐Abl

USP7 promotes non‐small‐cell lung cancer cell glycolysis and survival by stabilizing and activating c‐Abl

Abstract Background Abelson tyrosine kinase (c‐Abl) is frequently mutated and highly expressed, and promotes non‐small‐cell lung cancer (NSCLC) survival, metastasis and tumorigenesis. c‐Abl could also be modified through ubiquitination, but the underlying mechanism is not well understood. Methods Ma...

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Bibliographic Details
Main Authors: Yuanming He, Shuoyi Jiang, Yueya Zhong, Xiaoge Wang, Yaoli Cui, Jingpei Liang, Yuening Sun, Zhigang Zhu, Zhenqian Huang, Xinliang Mao
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Clinical and Translational Medicine
Subjects:
c‐Abl
hexokinase‐2
non‐small‐cell lung cancer
the ubiquitin‐proteasomal pathway
USP7
Online Access:https://doi.org/10.1002/ctm2.1509

Internet

https://doi.org/10.1002/ctm2.1509

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