Oral supplementation with selected Lactobacillus acidophilus triggers IL-17-dependent innate defense response, activation of innate lymphoid cells type 3 and improves colitis

Abstract Live biotherapeutic products constitute an emerging therapeutic approach to prevent or treat inflammatory bowel diseases. Lactobacillus acidophilus is a constituent of the human microbiota with probiotic potential, that is illustrated by improvement of intestinal inflammation and antimicrob...

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Bibliographic Details
Main Authors: Jiří Hrdý, Aurélie Couturier-Maillard, Denise Boutillier, Carmen Lapadatescu, Philippe Blanc, Jan Procházka, Bruno Pot, Bernhard Ryffel, Corinne Grangette, Mathias Chamaillard
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-21643-0