Increased adiposity, dysregulated glucose metabolism and systemic inflammation in Galectin-3 KO mice.

Increased adiposity, dysregulated glucose metabolism and systemic inflammation in Galectin-3 KO mice.

Obesity and type 2 diabetes are associated with increased production of Galectin-3 (Gal-3), a protein that modulates inflammation and clearance of glucose adducts. We used Lean and Diet-induced Obese (DIO) WT and Gal-3 KO mice to investigate the role of Gal-3 in modulation of adiposity, glucose meta...

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Bibliographic Details
Main Authors: Jingbo Pang, Davina H Rhodes, Maria Pini, Rand T Akasheh, Karla J Castellanos, Robert J Cabay, Dianne Cooper, Mauro Perretti, Giamila Fantuzzi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3579848?pdf=render

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http://europepmc.org/articles/PMC3579848?pdf=render

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