Interfering with the AKT/mTOR/STAT3/ID1 signaling axis with usenamine A restrains the proliferative and invasive potential of human hepatocellular carcinoma cells

Interfering with the AKT/mTOR/STAT3/ID1 signaling axis with usenamine A restrains the proliferative and invasive potential of human hepatocellular carcinoma cells

Abstract Background Usenamine A, a novel natural compound initially isolated from the lichen Usnea longissima, has exhibited promising efficacy against hepatoma in prior investigation. Nevertheless, the underlying mechanisms responsible for its antihepatoma effects remain unclear. Furthermore, the r...

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Bibliographic Details
Main Authors: Ailin Yang, Huiming Huang, Jinxin Xie, Yingying Tian, Longyan Wang, Dongxiao Liu, Xuejiao Wei, Peng Tan, Xingyun Chai, Xiaojun Zha, Pengfei Tu, Zhongdong Hu
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Chinese Medicine
Subjects:
Usenamine A
Hepatocellular carcinoma
AKT/mTOR/STAT3/ID1 axis
Proliferation
Invasion
Online Access:https://doi.org/10.1186/s13020-023-00875-w

Internet

https://doi.org/10.1186/s13020-023-00875-w

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