MAPK-activated protein kinase 2 is required for mouse meiotic spindle assembly and kinetochore-microtubule attachment.

MAPK-activated protein kinase 2 is required for mouse meiotic spindle assembly and kinetochore-microtubule attachment.

MAPK-activated protein kinase 2 (MK2), a direct substrate of p38 MAPK, plays key roles in multiple physiological functions in mitosis. Here, we show for the first time the unique distribution pattern of MK2 in meiosis. Phospho-MK2 was localized on bipolar spindle minus ends and along the interstitia...

Full description

Bibliographic Details
Main Authors: Ju Yuan, Bao-Zeng Xu, Shu-Tao Qi, Jing-Shan Tong, Liang Wei, Mo Li, Ying-Chun Ouyang, Yi Hou, Heide Schatten, Qing-Yuan Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2893158?pdf=render

Internet

http://europepmc.org/articles/PMC2893158?pdf=render

Similar Items